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早产儿维生素E储备不足,喂养困难、疾病等原因常导致其生后维生素E的摄入不能满足生理需要,供需不平衡状态与氧化应激性疾病之间存在的不良循环使早产儿维生素E缺乏趋于明显。早产儿维生素E缺乏可出现水肿、溶血性贫血、血小板增多等。大多数早产儿和几乎所有极低出生体重儿、超低出生体重儿均会发生贫血,早产儿生后4~8周血红蛋白浓度可降至65~90 g/L。目前普遍提倡生后早期补充维生素E辅助治疗早产儿贫血,虽然补充维生素E的剂型、时机、疗程及剂量已有报
Premature children lack of vitamin E reserves, feeding difficulties, diseases and other causes often lead to vitamin E intake after birth can not meet the physiological needs, imbalance between supply and demand and oxidative stress diseases exist between the poor circulation of premature children vitamin E deficiency Tends to be obvious. Premature children with vitamin E deficiency may appear edema, hemolytic anemia, thrombocytosis and so on. Most preterm children and almost all very low birth weight infants, low birth weight infants will have anemia, 4 to 8 weeks after birth, hemoglobin concentration can be reduced to 65 ~ 90 g / L. At present, it is generally advocated that vitamin E supplementation in the early postnatal period will help treat anemia in preterm infants. Although the dosage form, timing, course of treatment and dosage of vitamin E supplement have been reported