论文部分内容阅读
目的:比较不同治疗模式对胰腺癌的疗效。方法:分析2008年1月—2011年2月收治的100例胰腺癌患者资料,其中30例采用单纯手术治疗(手术治疗组),30例采用化疗治疗(化疗组),30例采用手术切除联合化疗治疗(联合治疗组),另10例采取其他治疗方法治疗(其他方法治疗组)。比较各组患者经治疗后的的生存情况,及不良反应发生情况。结果:手术治疗组、化疗组、联合治疗组、其他方法治疗组的中位生存期分别为(13.77±1.44),(11.95±1.60)(17.26±1.44),(2.89±1.46)个月,联合治疗组的生存情况明显优于其余各组(χ2=45.96,P=0.000);联合治疗组的总体不良反应发生率(3.33%)明显低于手术治疗组(26.67%),化疗组(30.00%),其他方法治疗组(30.00%)(χ2=8.178,P=0.04)。结论:应根据胰腺癌患者具体情况选择合适的治疗措施,以手术为主的综合治疗仍是最有效的手段。
Objective: To compare the curative effects of different treatment modalities on pancreatic cancer. Methods: The data of 100 patients with pancreatic cancer admitted from January 2008 to February 2011 were analyzed. Among them, 30 cases were treated with surgery alone (surgery group), 30 cases were treated with chemotherapy (chemotherapy group), 30 cases were treated with surgical resection Chemotherapy (combination therapy group), and the other 10 patients treated with other treatments (other treatment groups). Compare the survival of each group after treatment, and the occurrence of adverse reactions. Results: The median survival time was (13.77 ± 1.44), (11.95 ± 1.60) (17.26 ± 1.44) and (2.89 ± 1.46) months respectively in the surgery group, the chemotherapy group, the combination therapy group and the other treatment groups, Survival of the treatment group was significantly better than the other groups (χ2 = 45.96, P = 0.000); the incidence of adverse reactions in the combination group was significantly lower than that in the surgery group (3.66% ), Other methods of treatment group (30.00%) (χ2 = 8.178, P = 0.04). Conclusions: Appropriate treatment should be selected according to the specific conditions of patients with pancreatic cancer. Comprehensive treatment based on surgery is still the most effective method.