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目的:对乌司他丁治疗重度脓毒血症临床疗效进行观察研究。方法:随机选取2014年5月至2015年5月时间范围本院接收的50例重度脓毒血症患者,将其划分为研究组与对照组,各25例,对照组接受常规临床治疗,研究组在对照组基础上接受乌司他丁治疗,就两个组别的临床疗效进行观察对比。结果:研究组平均住院时长、好转率相较于对照组显著不同,研究组治疗后1d、3d、5dAPACHEII评分相较于对照组显著更低,数据差异具备统计学意义(P<0.05)。结论:乌司他丁应用于治疗重度脓毒血症疗效满意,可有效缓解患者痛苦,安全可靠,具备临床借鉴普及意义。
Objective: To observe the curative effect of ulinastatin on severe sepsis. Methods: Fifty patients with severe sepsis received in our hospital from May 2014 to May 2015 were selected randomly and divided into study group and control group, 25 cases in each group. The control group received routine clinical treatment. The group received ulinastatin treatment on the basis of the control group, the clinical efficacy of the two groups were observed and compared. Results: The mean length of hospital stay and the rate of improvement in the study group were significantly different from those in the control group. The APACHEII scores of the study group at 1, 3 and 5 days after treatment were significantly lower than those of the control group, with statistical significance (P <0.05). Conclusion: Ulinastatin is effective in treating severe sepsis, which can effectively relieve the patient ’s suffering, be safe and reliable, and have universal clinical significance.