A report on paraneoplastic motor neuron disease

• 作 者: Man-Ge Liu Jing-Wen Niu Li-Yin
• 机 构: Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Be
• 出 处: 中华医学杂志（英文版）
• 发表日期: 2019年6期
• 关键词: signs and symptoms

To the Editor:Motor neuron disease (MND) is marked by upper (UMN) or lower (LMN) motor neuron signs and symptoms,[1] which in various combinations form the basis for MND classification.In this regard,amyotrophic lateral sclerosis (ALS) is the most common subtype[2] Although otherwise deemed an untreatable degenerative disease,there is now increasing evidence of more heterogeneous pathogenesis,signaling a link between MND and paraneoplastic syndromes.[3]