论文部分内容阅读
目的探讨阿魏胶囊对高脂血症大鼠及家兔的预防作用。方法将家兔及大鼠随机分为模型组,阿魏胶囊低、中、高剂量组,辛伐他汀片组和正常对照组。正常对照组给予普通饮食,其余各组给予高脂饮食,同时给药组分别在给药4周和7周后,测定胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标。结果阿魏胶囊组可降低血清TC、TG、LDL-C,升高血清HDL-C/TC比值,与模型组相比差异有统计学意义(P<0.05)。结论阿魏胶囊对高脂血症大鼠及家兔有明显预防作用。
Objective To investigate the preventive effect of Awei capsule on hyperlipidemic rats and rabbits. Methods Rabbits and rats were randomly divided into model group, low-, medium-, high-dose Awei capsule group, simvastatin tablet group and normal control group. The normal control group was given an ordinary diet, and the remaining groups were given a high-fat diet. The cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDL) were measured in the administration group after 4 weeks and 7 weeks of administration, respectively. -C) Low-density lipoprotein cholesterol (LDL-C) and other indicators. [Results] The Aiwei Capsule group can reduce serum TC, TG, and LDL-C levels and increase the serum HDL-C/TC ratio. There was a statistically significant difference compared with the model group (P<0.05). Conclusion Awei capsule has obvious preventive effect on hyperlipidemic rats and rabbits.