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对50例冠心病患者及50例健康人血脂及载脂蛋白进行了测定。结果:冠心病患者血清TC,apo-C_3与健康人无显著差异;TG,apo-B100,apo-B100/apo-A_1比值均显著高于健康人(P<0.01);apo-A_1、apo-C_2均显著低于健康人(P<0.01)。血脂正常的冠心病患者apo-B100、apo-B100/apo-A_1比值也显著高予健康人(P<0.01);apo-A_1、apo-C_2也显著低于健康人(P<0.01)。表明检测载脂蛋白比血脂能更好地预测冠心病,血清apo-B100/apo-A_1比值是鉴别有无冠心病的最好指标。
Serum lipids and apolipoproteins in 50 patients with coronary heart disease and 50 healthy people were measured. Results: The serum levels of TC, apo-C_3 in patients with coronary heart disease were not significantly different from those in healthy people. The ratios of apo-B100, apo-B100 / apo-A_1 were significantly higher than those in healthy people C_2 were significantly lower than healthy people (P <0.01). The ratio of apo-B100 and apo-B100 / apo-A_1 was also significantly higher in healthy subjects with normal blood lipids (P <0.01). The apo-A 1 and apo-C 2 levels were also significantly lower in healthy subjects (P <0.01). Show that detecting apolipoprotein can better predict coronary heart disease than serum lipid. The ratio of serum apo-B100 / apo-A_1 is the best indicator of coronary heart disease.