扩血管药物治疗肺动脉高压的研究近况

• 作 者: 庄韵芳 黄定九 胡炳熊
• 机 构: 上海第二医科大学附属仁济医院,上海第二医科大学附属仁济医院,上海第二医科大学附属仁济医院,
• 出 处: 国外医学.心血管疾病分册
• 发表日期: 1987年02期
• 关键词: 肺动脉高压 体循环动脉 肺血管阻力 动脉弹性 小静脉 静脉瓣 扩血管药物 心输出量 肺毛细血管 肺动脉压力

一、概述:肺循环在结构上有以下几个特点:(1)与直径相同的体循环动脉相比,肺动脉弹性组织更多,而肌层则较薄;(2)肺毛细血管前小动脉和其后的小静脉几乎没有平滑肌成份,而这些成份在体循环是决定体循环血压的因素之一;(3)肺循环的静脉和小静脉内没有静脉瓣;(4)肺循环虽然受到丰富的外周神经支配,但这些神经在控制和调节肺血管阻力,流量及压力方面的作用很小.鉴于这些

First, an overview: The pulmonary circulation in the structure has the following characteristics: (1) with the same diameter of the systemic artery compared to more elastic tissue of the pulmonary artery, while the muscular layer is thin; (2) pulmonary capillary artery and its The posterior venules have almost no smooth muscle components, and these components in the systemic circulation is one of the factors that determine the systemic blood pressure; (3) there is no venous valve in the pulmonary circulation veins and venules; (4) although the pulmonary circulation is rich in peripheral nerve innervation, These nerves do little to control and regulate pulmonary vascular resistance, flow and pressure. Given these