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随着我国人口老龄化进程的加快,中老年人口的增加以及生活水平的提高,我国已进入老龄社会,对中老年男性健康和生活质量问题的研究已经逐渐受到重视。中老年男性部分雄激素缺乏综合征(PADAM)作为影响中老年男性健康的一种综合征,目前国内外多采用睾酮补充治疗,但是雄激素补充治疗引起的红细胞增多、前列腺增生以及前列腺癌的潜在影响也引起人们的密切关注,影响了雄激素补充治疗的临床应用。一些研究发现,许多营养素与人体的生殖功能、精子发生、雄激素合成与分泌都有一定的关系,尤其是维生素A、维生素E、微量元素锌和硒。本文主要从微营养素对PADAM的作用方面进行综述。
With the acceleration of population aging in our country, the increase of middle-aged and elderly population and the improvement of living standards, our country has entered into the aging society and the research on the health and quality of life of the middle-aged and elderly men has gradually been taken seriously. Partial androgen deficiency syndrome (PADAM) in middle-aged and old men is a syndrome that affects the health of middle-aged and old men. At present, more and more testosterone supplementation is used at home and abroad, but the potential of androgen replacement therapy to cause increased red blood cells, benign prostatic hyperplasia and prostate cancer The impact also aroused the close attention of people, affecting the clinical application of androgen replacement therapy. Some studies have found that many nutrients and the human reproductive function, spermatogenesis, androgen synthesis and secretion have a certain relationship, especially vitamin A, vitamin E, trace elements of zinc and selenium. This article reviews the role of micronutrients in PADAM.