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目的 研究隐睾发生的危险因素。方法 采用以医院为基础的 1∶2配比的病例对照研究方法 ,按统一的调查方法对 99例隐睾及 198例对照进行面对面问卷调查 ,应用SAS6 .12软件对所调查因素进行单因素及多因素logistic回归分析。 结果 胎儿隐睾与母亲孕早期感冒伴发热 (OR =9.37,95 %CI:2 .2 5~ 39.0 9) ,孕期发生先兆流产 (OR =4 .6 6 ,95 %CI :2 .0 2~ 10 .74 ) ,孕期发生先兆子痫 (OR =16 .33,95 %CI:1.4 0~ 191.2 0 ) ,父亲职业性接触农药 (OR =12 .79,95 %CI:2 .90~5 6 .4 3) ,低出生体重 (OR =5 .77,95 %CI:1.39~ 2 3.98) ,母亲怀孕年龄 <2 4岁 (OR =2 .89,95 %CI :1.2 9~ 4 .0 6 )呈正相关。结论 母亲孕早期感冒伴发热 ,孕期发生先兆流产及先兆子痫 ,父亲职业性接触农药 ,低出生体重 ,母亲怀孕年龄 <2 4岁是隐睾发病的主要危险因素。
Objective To study the risk factors of cryptorchidism. Methods A hospital-based 1: 2 ratio case-control study was conducted. According to a uniform survey method, 99 cases of cryptorchidism and 198 controls were investigated by face-to-face questionnaire. SAS6.12 software was used to investigate the single factor and Multivariate logistic regression analysis. Results Fetal cryptorchidism was associated with fever in the first trimester of pregnancy (OR = 9.37, 95% CI: 2.52 ~ 39.0 9), threatened abortion during pregnancy (OR = 4.6.6 95% CI: 10.74), preeclampsia (OR = 16.33, 95% CI: 1.4 0-119.2 0) during pregnancy, and occupational exposure to pesticides (OR = 12.79, 95% CI: 2.90-56 .4 3), low birth weight (OR = 5.77, 95% CI: 1.39-2.298), maternal age <2-4 (OR = 2.89, 95% CI: 1.2 9-4.06 ) Was positively correlated. Conclusion The mothers with early pregnancy cold and fever, threatened abortion during pregnancy and preeclampsia, occupational exposure to pesticides and low birth weight in mothers, and the pregnant age <24 was the main risk factor for cryptorchidism.