Microbial translocation,residual viremia and immune senescence in the pathogenesis of HIV-1 infectio

• 作 者: Alessandra Fantauzzi Francesca
• 机 构: DepartmentofClinicalMedicine,DepartmentofMolecularMedicine,DepartmentofPublicHealthandInfectiousDise
• 出 处: 世界临床传染病学杂志
• 发表日期: 2013年4期
• 关键词: Human IMMUNODEFICIENCY virus-1 Combined ANTIRETROVIRAL therapy IMMUNE activation

The pathophysiological mechanisms that underlie the progression of human immunodeficiency virus-1(HIV-1)disease to full-blown AIDS are not well understood.Findings suggest that,during HIV-1 infection,plasma lipopolysaccharide(LPS)levels,which are used as