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目的探讨癫痫病人血浆和ＣＳＦ中生长抑素（ＳＳ）的浓度及其临床意义。方法采用放射免疫法（ＲＩＡ）测定２７例癫痫病人和１２例正常对照组之血浆和ＣＳＦ样品。结果癫痫病人血浆和ＣＳＦ中ＳＳ浓度明显低于对照组。３天内有癫痫发作病人血浆和ＣＳＦ中ＳＳ浓度明显低于３天内无发作病人（Ｐ均＜００１）。结论癫痫病人血浆和ＣＳＦ中的ＳＳ改变与癫痫的发作和病程密切相关
Objective To investigate the concentration of somatostatin (SS) in plasma and CSF of epileptic patients and its clinical significance. Methods Radioimmunoassay (RIA) was used to detect plasma and CSF samples from 27 patients with epilepsy and 12 normal controls. Results The concentration of SS in plasma and CSF of epileptic patients was significantly lower than that of the control group. SS concentrations in plasma and CSF of patients with seizures within 3 days were significantly lower than those without seizures within 3 days (all P <001). Conclusion SS in plasma and CSF of epileptic patients is closely related to the onset and duration of epilepsy