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目的研究分析红景天对慢性间质性肾炎患者血清TGF-β1的影响和临床应用价值。方法选取2012年1月~2014年1月我院收治的204例慢性间质性肾炎患者,将其分为观察组103例,对照组101例,对照组应用传统的口服强的松治疗,观察组在对照组的基础上口服红景天,两组治疗周期3个月,同时选取25例正常人作为健康组,分别对三组治疗前后的TGF-β1和24h尿蛋白值进行监测,并对比分析。结果在治疗3个月后,观察组患者的TGF-β1和24h尿蛋白明显低于对照组,两组比较P<0.05为差异有统计学意义;观察组患者治疗后TGF-β1和24h尿蛋白接近于健康组人群。结论红景天在慢性间质性肾炎患者的治疗中有显著的调整作用,并且价格低廉、应用方便,副作用小,具有良好的临床应用价值。
Objective To study the effect of rhodiola on the serum TGF-β1 in patients with chronic interstitial nephritis and its clinical value. Methods From January 2012 to January 2014, 204 patients with chronic interstitial nephritis admitted to our hospital were divided into observation group (n = 103) and control group (n = 101). The control group was treated with traditional oral prednisone and observed The patients were given Rhodiola orally on the basis of the control group. The two groups were treated for 3 months. At the same time, 25 healthy individuals were selected as the healthy group. The levels of TGF-β1 and 24h urine protein before and after treatment were monitored, analysis. Results After 3 months of treatment, the levels of TGF-β1 and 24h urinary protein in the observation group were significantly lower than those in the control group, P <0.05 was considered as significant difference between the two groups. After treatment, TGF-β1 and 24h urinary protein Close to the healthy group of people. Conclusion Rhodiola rosea in patients with chronic interstitial nephritis in the treatment of significant adjustment, and the low price, easy to use, side effects, has good clinical value.