论文部分内容阅读
为研究围产期嗜神经病毒感染与脑瘫发生的关系,Gibson及其同事对南澳地区的新生儿进行了病例对照研究,研究包括443名脑瘫患儿和883 名对照,对照组与患儿在出生时间、地点、采血时间等方面相匹配,因脑瘫患儿早产及产于大城市教学医院的比例较高,故对照早产及产于大城市教学医院的比例亦高于普通人群。采用多聚酶链反应对新生儿血样中的肠病毒和疱疹病毒核酸进行检测,其中A类疱疹病毒包括单纯疱疹病毒1(HSV- 1)、单纯疱疹病毒2(HSV-2)、Epstein- Barr病毒(EB病毒)、巨细胞病毒 (CMV)和人类疱疹病毒8(HHV-8);B 类疱疹病毒包括水痘-带状疱疹病毒 (VZV)、人类疱疹病毒6(HHV-6)和人类疱疹病毒7(HHV-7)。
To study the relationship between perinatal neuropharyngeal virus infection and cerebral palsy, Gibson and colleagues conducted a case-control study of neonates in South Australia, including 443 children with cerebral palsy and 883 controls, and controls and children at birth Time, location, blood collection time and other aspects of matching, due to cerebral palsy children premature delivery and produced in the city teaching hospital a higher proportion of preterm birth and produced in the teaching hospital in the city is also higher than the proportion of the general population. Detection of enterovirus and herpesvirus nucleic acids in neonatal blood samples by polymerase chain reaction, including herpes simplex virus 1 (HSV-1), herpes simplex virus 2 (HSV-2), Epstein-Barr virus Epstein-Barr virus), cytomegalovirus (CMV) and human herpesvirus 8 (HHV-8); herpesvirus B including varicella-zoster virus (VZV), human herpes virus 6 (HHV-6) and human herpesvirus 7 (HHV-7).