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目的观察多极射频消融(RFA)联合经导管肝动脉栓塞化疗(TACE)治疗巨块型肝癌的临床效果。方法选取2012年10月-2016年7月到医院参与治疗的巨块型肝癌患者40例,随机分为观察组与对照组各20例。对照组给予单纯TACE治疗,观察组采用多极RFA联合TACE治疗,比较2组患者临床治疗效果及治疗前后甲胎蛋白(AFP)水平变化情况。结果观察组治疗有效率为80.0%明显高于对照组的60.0%;治疗后2组患者血清AFP水平明显低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论巨块型肝癌患者采用多极RFA联合TACE治疗效果显著,值得广泛推广。
Objective To observe the clinical effect of multi-polar radiofrequency ablation (RFA) combined with transcatheter hepatic arterial chemoembolization (TACE) in the treatment of massive liver cancer. Methods From October 2012 to July 2016, 40 patients with massive liver cancer who participated in the hospital were randomly divided into observation group and control group with 20 cases each. The control group was treated with simple TACE. The observation group was treated with multi-polar RFA combined with TACE. The clinical effect and the level of AFP in both groups were compared. Results The effective rate of observation group was 80.0%, which was significantly higher than that of the control group (60.0%). The AFP levels of two groups were significantly lower than those before treatment, and the difference was statistically significant (P <0.05 ). Conclusion The treatment of massive liver cancer patients with multi-polar RFA combined TACE effect is significant, it is worth widely disseminated.