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肺结核病疗程长,有的病人因经济负担重,往往难以全程、规则治疗,而成为复治、难治病例。我所于1984年8月～1986年2月,以12HT(T组)与12HE(E组)方案对初治菌阳病人随机分组用药,对照比较。结果观察96例,资料完整91例,其中T组49例,E组42例:男性54例,女性37例;平均年龄43.9岁,最小17岁,最大64岁;有空洞19例,其中T组10例,E组9例。T组痰菌阴转率85.71％(42/49),E组为88.09％(37/42),无显著性差异(P>0.05)。3.副反应:主要有消化道症状、肝损、皮疹、神经炎,T组分别为13例(26,53),3例(6.12％),4例(8.16％),2例(4.08％);E组分别为5例(11.90％),2例
Tuberculosis long course of treatment, and some patients due to economic burden, it is often difficult to full, the rule of treatment, and become retreatment, refractory cases. I was in August 1984 ~ February 1986, 12HT (T group) and 12HE (E group) regimen of newly diagnosed bacillary positive patients randomized to compare. The results were observed in 96 cases, complete data 91 cases, of which 49 cases of T group, E group of 42 cases: 54 males and 37 females; mean age 43.9 years, minimum 17 years old, maximum 64 years; 10 cases, E group 9 cases. The sputum negative conversion rate was 85.71% (42/49) in group T and 88.09% (37/42) in group E, with no significant difference (P> 0.05). 3. Side effects: mainly gastrointestinal symptoms, liver damage, rash, neuritis, T group were 13 cases (26,53), 3 cases (6.12%), 4 cases (8.16%), 2 cases (4.08% ); E group were 5 cases (11.90%), 2 cases