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目的对比研究支气管哮喘患者不同炎症表型的临床特征。方法选取2010年1月—2012年12月在昌平区中西医结合医院就诊的哮喘患者302例,依据诱导痰炎症细胞分类结果对患者进行分组,对不同组别患者的进行研究。结果不同炎症表型哮喘患者的病情、呼吸道感染、白细胞比较、BMI、静脉血Eos数目比较,差异有统计学意义(P<0.05);不同炎症表型哮喘患者治疗前肺功能比较,除FEV1%预计值外,其他指标比较,差异均无统计学意义(P>0.05)。结论哮喘患者存在不同的炎症表型,但其临床特征差异并不大。
Objective To compare the clinical features of different inflammatory phenotypes in patients with bronchial asthma. Methods From January 2010 to December 2012, 302 patients with asthma were selected from the Integrative Medicine Hospital of Changping District. Patients were divided into groups based on the classification results of induced sputum inflammatory cells, and the patients in different groups were studied. Results There were significant differences in respiratory tract infection, white blood cell count, BMI, and Eos in venous blood among patients with different inflammatory phenotype asthma (P <0.05) Expected value, the other indicators, the difference was not statistically significant (P> 0.05). Conclusion There are different inflammatory phenotypes in patients with asthma, but the clinical features are not different.