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目的:探讨子痫前期患者血尿酸的变化对围产儿的影响和预测妊娠预后。方法:通过测定181例子痫前期患者血尿酸含量,并选择100例正常单胎妊娠孕妇作为对照。结果:随着孕周的增加,血尿酸值升高;子痫前期患者血尿酸值明显高于正常妊娠组,差异具有显著性意义。随着血尿酸值升高,新生儿体重降低,FGR发生率增加,预后不良率逐渐升高。结论:随着血尿酸值升高,对胎儿生长发育负影响越大。当血尿酸值>400μmol/L,预警胎儿情况危急,须严密观察监护适时结束分娩。
Objective: To investigate the effect of changes of serum uric acid in preeclampsia on perinatal children and predict the prognosis of pregnancy. Methods: Determination of serum and uric acid levels in 181 preeclampsia patients, and select 100 cases of normal singleton pregnant women as a control. Results: With the increase of gestational age, serum uric acid increased; the serum uric acid in preeclampsia patients was significantly higher than that in normal pregnant women, the difference was significant. With the rise of serum uric acid value, neonatal weight loss, FGR increased the incidence of poor prognosis increased gradually. Conclusion: With the increase of serum uric acid value, the greater negative impact on fetal growth and development. When the serum uric acid value> 400μmol / L, the critical situation of the fetus to be alert, close observation of custody should be timely end of childbirth.