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目的采用256层螺旋CT血管造影(CTA)定量研究冠状动脉迂曲与冠心病发生率相关性并进一步探讨其临床价值。方法对1275例拟诊冠心病患者行冠状动脉CTA,其中男693例,女582例,年龄33～78岁,平均(57.65±12.35)岁。统计冠状动脉狭窄程度及冠状动脉迂曲发生率,分析两者间的关系,并观察其与性别的关系。结果 1275例行冠状动脉CTA患者中,冠状动脉狭窄(狭窄程度≥50%)患者336例,其中男219例(17.2%),女117例(9.2%)。冠状动脉迂曲患者441例,其中男188例(14.7%),女253例(19.8%)。冠状动脉迂曲组在不同冠状动脉狭窄程度及多支中重度狭窄时,狭窄发生率均低于无迂曲组(P值均<0.05)。结论 256层螺旋CTA可以客观显示冠状动脉的迂曲和狭窄,冠状动脉的迂曲和狭窄均引起了血流动力学的改变,两者之间具有相关性,冠状动脉迂曲可以降低冠状动脉狭窄的发生率及程度。
Objective To quantitatively study the relationship between coronary artery tortuosity and the incidence of coronary heart disease (CAD) with 256-slice spiral CT angiography (CTA) and to explore its clinical value. Methods CTA was performed in 1,275 patients with suspected coronary heart disease, including 693 males and 582 females, aged 33-78 years, with an average of (57.65 ± 12.35) years. The degree of coronary artery stenosis and the incidence of coronary artery tortuosity were analyzed. The relationship between the two and the relationship between them were also analyzed. Results Of the 1275 patients with coronary artery CTA, 336 patients had coronary artery stenosis (stenosis ≥50%), including 219 males (17.2%) and 117 females (9.2%). There were 441 patients with tortuous coronary arteries, including 188 males (14.7%) and 253 females (19.8%). Coronary artery tortuosity in different degrees of coronary stenosis and multiple stenosis, the incidence of stenosis were lower than those without tortuous group (P <0.05). Conclusion The 256-slice spiral CTA can objectively show tortuosity and stenosis of coronary arteries, tortuosity and stenosis of coronary arteries have caused hemodynamic changes, the correlation between the two is that coronary tortuosity can reduce the incidence of coronary artery stenosis And the degree.