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本文结合审评中发现的问题,对相对分子质量及其分布测定在中药多糖有效部位研究中的重要作用及应关注的问题进行了分析,建议采用HPGPC方法进行测定,并与文献及其他方法进行比较研究,相互印证结果。
Based on the problems found in the review, this paper analyzes the important role of molecular weight and its distribution in the study of effective fractions of polysaccharides in Chinese traditional medicine and the problems that should be paid attention to. It is suggested that HPGPC method should be used to determine the relative molecular mass and its distribution. Compare and verify each other’s results.