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目的 探讨中晚期肝癌 (hepatocellularcarcinoma ,HCC)经皮穿刺肝动脉化疗栓塞 (tran shepaticarterychemoembolization ,TACE)联合集束电极射频 (radiofrequency ,RF)的治疗效果。 方法 3 2例HCC病人在TACE 2～ 3周后行RF治疗 (联合组 )与同期经二次TACE的 3 4例 (TACE组 )比较。结果 联合组在瘤体缩小 (P <0 0 1)、AFP下降、自觉症状改善等方面好于TACE组 ,且骨髓抑制少 (P <0 0 5 ) ,肝功能损害轻 (P <0 0 1)。结论 TACE联合RF治疗中晚期肝癌 ,具有相互加强作用 ,是一种有效的联合治疗方法
Objective To investigate the therapeutic effect of transepithelial arterial chemoembolization (TACE) and cluster electrode radiofrequency (RF) on advanced hepatocellular carcinoma (HCC). METHODS: Twenty-two patients with HCC underwent RF therapy 2 to 3 weeks after TACE (combination group) and 34 patients underwent TACE during the same period (TACE group). Results The combination group was better than TACE group in shrinking the tumor (P <0.01), decreasing the AFP and improving the symptoms, and had less bone marrow suppression (P <0.05) and less liver damage (P <0.01) ). Conclusion TACE combined with RF in the treatment of advanced hepatocellular carcinoma has the effect of strengthening each other and is an effective combination therapy