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[问]应用苯氧乙醇局部湿敷治疗绿脓杆菌感染创面,其浓度和用量多大才合适?能否用纯溶液(含量99%)湿敷?如果用了而且量较大(超过1,000毫升),有没有毒性作用?临床表现如何?[答]苯氧乙醇(Phenoxyaethanolum)是无色略带玫瑰香味稍有粘性的液体。20℃时在水中的溶解度为2~5%,pH6.4~6.5。能与酒精、丙酮及甘油相混合。苯氧乙醇在不同温度条件下的杀菌浓度见下表:
[Q] Application of phenoxyethanol local wet compress treatment of Pseudomonas aeruginosa infection wound, the concentration and amount of how appropriate? Can pure solution (content 99%) wet compress? If used and the amount of large (more than 1,000 ml) , Has no toxic effect? What is the clinical manifestations? [Answer] Phenoxyethanol (Phenoxyaethanolum) is a colorless slightly rosy aroma slightly viscous liquid. The solubility in water at 20 ℃ is 2 ~ 5%, pH6.4 ~ 6.5. With alcohol, acetone and glycerol mixed. Phenoxyethanol at different temperatures under the bactericidal concentration in the table below: