论文部分内容阅读
目的观察A型肉毒毒素治疗眼睑及面肌痉挛的效果。方法选择38例中度、重度眼睑及面肌痉挛患者,应用A型肉毒毒素局部注射治疗。结果随访6个月~3年,其中30例患者症状完全缓解;7例明显缓解,1例无效。37例患者均在注射后3~4个月复发。复发的37例,28例选择重复注射,所有注射A型肉毒毒素的患者均未出现全身副作用,但注射后20例患者(55.6%)出现不同程度的干眼,角膜点状染色。结论 A型肉毒毒素局部注射治疗中、重度眼睑及面肌痉挛安全、有效。但应注意在注射前后检查眼表情况,注射后常规使用人工泪液。
Objective To observe the effect of botulinum toxin A in the treatment of eyelid and hemifacial spasm. Methods Thirty-eight patients with moderate and severe eyelid and hemifacial spasm were selected and treated with local injection of botulinum toxin type A. The results were followed up for 6 months to 3 years, of which 30 patients with complete remission of symptoms; 7 patients were relieved, 1 was ineffective. All 37 patients relapsed 3 to 4 months after injection. Of the 37 patients who relapsed, 28 received repeated injections. All patients with botulinum toxin A had no systemic side effects, but 20 (55.6%) had dry-point and corneal punctate staining after injection. Conclusion Botulinum toxin A is safe and effective in the treatment of moderate and severe eyelid and hemifacial spasm. However, attention should be paid before and after the injection of ocular surface examination, routine use of artificial tears after injection.