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离乳Balb/c小鼠48只,按性别体重随机分成缺锌、对饲对照及自由进食对照三大组,每大组又分成运动和不运动两组。6周后进行锌、铜、丙二醛(MDA)、超氧化物歧化酶(SOD)、谷光甘肽过氧化物酶(GSH-Px)及过氧化氢酶(CAT) 的测定,并对肝组织直接进行低温ESR(电子自旋共振)波谱分析。实验结果提示:锌缺乏将导致运动及不运动小鼠体内的自由基生成增加和清除减少;运动训练虽可使正常小鼠体内的自由基防御能力加强,但却对锌缺乏小鼠体内的SOD、GSH-Px和CAT均无显著作用,相反,运动训练还可以使缺锌小鼠肝线粒体内的脂质过氧化产物进一步显著增加。
Forty eight Balb / c mice were randomly divided into three groups according to their sex and weight: zinc deficiency, feeding control and free feeding control. Each group was divided into two groups: exercise and no exercise. After 6 weeks, the contents of zinc, copper, malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) Tissue is directly subjected to low temperature ESR (electron spin resonance) spectroscopy. The results suggest that: zinc deficiency will lead to exercise and no exercise to increase the production of free radicals and reduce clearance; exercise training may make the normal mice in vivo defense ability of free radicals, but zinc deficiency in mice in vivo SOD , GSH-Px and CAT had no significant effect. On the contrary, exercise training could further significantly increase the lipid peroxidation products in the liver mitochondria of zinc deficient mice.