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目的研究瘤果黑种草子提取物(油脂、非油脂)对支气管平滑肌的解痉作用。方法采用小鼠喷雾致喘实验、豚鼠肺支气管灌流法及离体回肠实验考察瘤果黑种草子提取物对支气管平滑肌解痉作用。结果瘤果黑种草子油脂和非油脂低剂量明显延长小鼠哮喘反应的潜伏期,增加豚鼠支气管肺灌流量,降低豚鼠回肠平滑肌收缩张力,与对照组比较,差异具有统计学意义(P<0.01)。结论瘤果黑种草子提取物(油脂、非油脂)对支气管平滑肌具有一定的解痉作用。
Aim To study the antispasmodic effect of the extract of kusnezoffii seed extract (oil and non-fat) on bronchial smooth muscle. Methods Spray asthma in mice experiments, guinea pig lung bronchial perfusion method and isolated ileum experiment to study the tumor of the fruit of the grass on the bronchial smooth muscle spasm. Results The results showed that the growth of asthma in mice was significantly prolonged and the bronchial lung perfusion was decreased and the contraction tension of guinea pig ileum smooth muscle was decreased. The difference was statistically significant (P <0.01) . Conclusion The tumor of the black grass seeds extract (oil, non-fat) on bronchial smooth muscle spasm.