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本文比较日摄盐量相近、有及无高血压家族史的5～6岁儿童的盐负荷前后尿钠排出量。结果表明,二组盐负荷前的尿钠量相近,差异无意义。后有家族史儿童的尿钠量明显较无家族史者为少。差异有高度显著意义(P<0.0001)。盐负荷后24小时尿钠与有关指标的逐步回归分析表明,家族史是影响尿钠排泄的重要因素。两组间盐负荷前后尿钠不同差值的人数分布比较表明,差值为负值时,二者间差异有显著意义(P<0.05)。建议以尿钠差值的负值作为原发性高血压先兆倾向的筛选标准。
In this paper, sodium salt excretion before and after salt loading was compared between children aged 5 ~ 6 years with similar daily salt intake and with and without a family history of hypertension. The results showed that there was no difference in the amount of natriuresis between the two groups before salt loading. After a family history of children with natriuresis significantly less than no family history. The difference was highly significant (P <0.0001). Stepwise regression analysis of urinary sodium and related indicators 24 hours after salt loading showed that family history was an important factor affecting urinary sodium excretion. The comparison of the distribution of urine sodium difference between the two groups before and after salt loading showed that there was a significant difference between the two groups when the difference was negative (P <0.05). Proposed negative urine sodium difference as a predictor of hypertension tendencies screening criteria.