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我国是病毒性肝炎的高发区，其中慢性乙型肝炎则是发展成肝硬化和肝癌的主要危险因素［１］。以往国外的临床资料表明，α干扰素是目前治疗乙型肝炎病毒最有希望的药物之一［２，３］。近年来国内也陆续报道了国产重组干扰素治疗乙型肝炎［４］。自１９９６年５月至１９９８
China is a high incidence of viral hepatitis, of which chronic hepatitis B is the development of cirrhosis and liver cancer is a major risk factor [1]. Previous foreign clinical data show that α interferon is currently the treatment of hepatitis B virus one of the most promising drugs [2,3]. In recent years, China has also reported the domestic recombinant interferon treatment of hepatitis B [4]. From May 1996 to 1998