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目的:探讨右美托咪定联合异丙酚对沿海船民无痛胃镜检查中的血流变指标的影响。方法:随机将来我院进行无痛胃镜检查的85例沿海船民分为两组,对照组采用异丙酚麻醉,观察组采用右美托咪定复合异丙酚麻醉,比较两组镇静效果、血流变指标及不良反应发生率。结果:观察组相比对照组的麻醉诱导时间、入睡时间、苏醒时间、定向力恢复时间及异丙酚用量都更低,比较差异有统计学意义(P<0.05)。观察组血流变指标相比对照组都更优,比较差异有统计学意义(P<0.05)。观察组相比对照组不良反应发生率更低,比较差异有统计学意义(P<0.05)。结论:右美托咪定复合异丙酚能有效提高镇静效果,降低应激反应,维持被检查者的血流变指标保持稳定。
Objective: To investigate the effect of dexmedetomidine combined with propofol on the indexes of hemorheology in painless gastroscopy of coastal boat people. Methods: In the future, 85 patients with painless gastroscopy in our hospital were randomized into two groups. The control group was given propofol anesthesia. The observation group was treated with dexmedetomidine combined with propofol. The sedation effect, Rheological indicators and the incidence of adverse reactions. Results: Compared with the control group, the induction time, sleep time, recovery time, recovery time of directional force and propofol dosage in the observation group were all lower than those in the control group (P <0.05). The indexes of hemorheology in observation group were better than those in control group, and the difference was statistically significant (P <0.05). The incidence of adverse reactions in observation group was lower than that in control group, with significant difference (P <0.05). Conclusion: Dexmedetomidine combined with propofol can effectively improve the sedation effect, reduce the stress response and maintain the hemorrheological indexes of the subjects to be stable.