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目的分析高频单味中药组方联合普罗布考治疗缺血性脑卒中对患者血清超敏C反应蛋白(hs-CRP)、妊娠相关血浆蛋白A(PAPP-A)水平的影响。方法将212例缺血性脑卒中患者随机分为试验组和对照组各106例。试验组采用高频单味中药组方联合普罗布考治疗,对照组仅给予普罗布考治疗。比较2组治疗前后血清hs-CRP及PAPP-A水平。结果治疗前2组患者血清hs-CRP及PAPP-A水平差异无统计学意义(P>0.05)。治疗后2组患者血清hs-CRP及PAPP-A水平均低于治疗前,且试验组低于对照组,差异均具有统计学意义(P<0.05)。结论高频单味中药组方联合普罗布考治疗缺血性脑卒中具有显著降低患者血清hs-CRP和PAPP-A水平的作用。
Objective To analyze the effects of single-high-frequency herbs combined with probucol on the serum hs-CRP and PAPP-A levels in patients with ischemic stroke. Methods 212 cases of ischemic stroke were randomly divided into experimental group and control group of 106 cases. The experimental group with high-frequency single herbs group combined with probucol treatment, the control group was given only probucol treatment. The serum hs-CRP and PAPP-A levels in two groups before and after treatment were compared. Results There was no significant difference in serum hs-CRP and PAPP-A levels between the two groups before treatment (P> 0.05). The serum hs-CRP and PAPP-A levels in two groups after treatment were lower than before treatment, and the experimental group was lower than the control group, the difference was statistically significant (P <0.05). Conclusion The single-high-frequency herbs combined with probucol in the treatment of ischemic stroke patients significantly reduce the serum hs-CRP and PAPP-A levels.