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1968年,在未接触过麻疹的格陵兰的斯科斯比松地区500人中,有460人接种了Sch-wartz麻疹减毒活疫苗。在接种前和接种后的16年间,应用IgM、IgA和IgG ELISA以及血凝抑制(HI)试验7次抽样测定麻疹抗体,部份样品用免疫印迹法测定。接种前55份血样无1份有IgM、IgG或HI麻疹抗体。接种后如以IgG和HI的结果判定,血清阳转率为94～100%。对lgM、IgA和IgG ELISA抗体随访了16
In 1968, 460 of the 500 people in the unclasped Koskirchen area of Greenland were vaccinated against live attenuated Schwartz measles vaccine. Measles antibodies were determined seven times before vaccination and 16 years after inoculation using IgM, IgA and IgG ELISA and HI tests, and some samples were determined by immunoblotting. None of the 55 blood samples before inoculation had IgM, IgG or HI measles antibodies. After inoculation as judged by the results of IgG and HI, the seroconversion rate was 94-100%. LgM, IgA and IgG ELISA antibodies were followed for 16