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乙型肝炎病毒感染能引起肝外其它器官系统异常,如血清病综合征、结节性多动脉炎、肾小球肾炎及混合性冷球蛋白血症等.各种HBV抗原(HBsAg、HBcAg、HBeAg)都可以IC的形式沉积于肝外组织中而引起肝外表现.在HBV感染时,致病的抗原可能是病毒本身的结构抗原,如HBsAg,也可能是在病毒基因物质作用下产生的新抗原.血清病综合征急性HBV感染的前驱症状有时表现为血清病样综合征,如发热、关节痛、荨麻疹.相当多的患者伴有对称性关节痛和关节炎,常伴有关节晨间僵硬,易被误诊为急性类风湿性关节
Hepatitis B virus infection can cause other extrahepatic organ system abnormalities, such as serum sickness syndrome, polyarteritis nodosa, glomerulonephritis and mixed cryoglobulinemia, etc .. A variety of HBV antigens (HBsAg, HBcAg, HBeAg) can be deposited in extrahepatic tissues in the form of IC causing extrahepatic manifestations.In the case of HBV infection, the pathogenic antigen may be the structural antigen of the virus itself, such as HBsAg, may also be produced by the viral genetic material New Antigens. Serum Syndrome Acute HBV infection is sometimes preceded by symptoms of seronegative disease such as fever, arthralgia and urticaria. A considerable number of patients are accompanied by symmetrical joint pain and arthritis, often accompanied by joint disease Between the rigid, easily misdiagnosed as acute rheumatoid joint