【摘 要】
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Dear Editor,Plants produce a large range of triterpenoids that serve as chemical defenses against pathogens.For example,β-amyrin synthase (AsbAS1) performs the
【机 构】
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Key Laboratory of Plant Molecular Physiology, Institute of Botany,Chinese Academy of Sciences, Nanxi
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Dear Editor,Plants produce a large range of triterpenoids that serve as chemical defenses against pathogens.For example,β-amyrin synthase (AsbAS1) performs the initial enzymatic step in the biosynthesis of the potent antimicrobial avencins in oats (Haralampidis et al.,2001).Additionally,other triterpenoids such as glycyrrhizin and QS21 are known to have beneficial or detrimental effects for human health (Osbou et al.,2011).For some time,heterologous expression of plant oxidosqualene cyclases (OSCs) in yeast has been a powerful methodology for the functional characterization of this important family of triterpene biosynthetic enzymes.The foundational work in this area employed the lanosterol-deficient Saccharomyces cerevisiae strain SMY1 to characterize the function of Arabidopsis thaliana cycloartenol synthase (CAS)(Corey et al.,1993).
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