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我们很难想象五十年代后期 Alec Isaacs 称之为“干扰素”的物质被发现并被初次描述的革命性意义(Isaacs等,1957)。对当时的许多人来说,它只是一个生动的科学幻想中的事物。但是,最初的那些观察还是被许多实验室仔细地重复;七十年代期间人们还或多或少承认了细胞产生的能说明病毒干扰现象的这种可溶性物质。发现干扰素的时候,就有人认识到可用它来干扰病毒的复制而并不一定会危及细胞的代谢作用,许多人还相信干扰素可能是一种
It is hard to imagine the revolutionary significance that the substance of what Alec Isaacs called the “interferon” in the late fifties was discovered and first described (Isaacs et al., 1957). For many at the time it was just a vivid science fantasy thing. However, the first observations were repeated carefully by many laboratories; in the 1970s, it was more or less acknowledged by cells that the soluble substances produced by cells were indicative of viral interference. Interferon was discovered when it was recognized that it can be used to interfere with the virus’s replication and does not necessarily endanger the metabolism of the cell, many people also believe that interferon may be a