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骨桥蛋白(osteopontin,OPN)作为一种多功能细胞因子和细胞外基质蛋白,广泛分布于多种组织和细胞中,参与多种病理过程。近年来,OPN在肺部疾病中的作用备受关注,本文就OPN与肺部疾病的研究进展综述如下。
As a multifunctional cytokine and extracellular matrix protein, osteopontin (OPN) is widely distributed in many tissues and cells and participates in many pathological processes. In recent years, the role of OPN in lung diseases has drawn much attention. The progress of OPN and lung diseases in this paper is summarized as follows.