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目的 探讨不同血源对ABO溶血病外周动静脉同步换血的疗效。方法 对 2 3例ABO溶血病患儿依时间分为二组 ,同型血组和混合血组。同型血组采用与患儿血型相同的血为血源换血 ,混合血组采用AB型血浆和O型洗涤红细胞混合血为血源换血。换血途径均采用外周动静脉。结果 同型血组和混合血组换血后总胆红素下降显著 ,4 50 0± 1 4 4 2 4 μmol/L ,2 54 56± 87 58μmol/L ,393 4 8± 1 6 7 4 6vs2 36 6 0± 97 79μmol/L ;两组的换出率分别是 :4 2 2 5± 1 3 91 % ,38 4 6± 1 3 1 6 % ,t =0 70 ,P >0 0 5。换血后两组的血细胞 ,红细胞压积 (HCT) ,电解质 ,白蛋白改变相同。换血后无明显不良反应。结论 同型血和混合血为血源换血疗效相同 ,在紧急情况下采用同型血换血可以节约时间。
Objective To investigate the curative effect of different blood sources on the synchronized exchange transfusion of ABO hemolytic disease peripheral arteriovenous. Methods 23 cases of children with ABO hemolytic disease were divided into two groups according to time, same blood group and mixed blood group. The same blood group and children with the same type of blood blood for blood exchange, mixed blood group using AB blood type and O-type mixed red blood cells for blood exchange transfusion. Transfusion methods are used peripheral arteriovenous. Results The levels of total bilirubin decreased significantly in transfused blood of the same blood group and mixed blood group, with a mean of 4 50 ± 1 442 4 μmol / L, 2 54 56 ± 87 58 μmol / L, 393 48 ± 1 6 7 4 6 vs 366 6 0 ± 97 79μmol / L; the exchange rates of the two groups were: 4 2 2 5 ± 1 3 91%, 38 4 6 ± 1 3 1 6%, t = 0 70, P 0 05. Blood transfusions after the two groups of blood cells, hematocrit (HCT), electrolyte, albumin change the same. No obvious side effects after transfusion. Conclusions Homoemesis and mixed blood have the same efficacy in blood exchange and blood transfusion, which can save time in the case of emergency.