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目的观察氨氯地平联合依那普利治疗原发性高血压的临床疗效。方法将我院收治的120例原发性高血压患者随机分成两组,对照组60例单纯使用氨氯地平治疗,治疗组60例在对照组的基础上加用依那普利治疗,4周为1个疗程,2个疗程后比较两组的疗效。结果治疗组的血压下降明显,总有效率93.3%,对照组的总有效率71.7%,两组相比较有统计学差异(P<0.05);治疗组的不良反应发生率为6.7%,对照组为15.0%,两组相比较有统计学差异(P<0.05)。结论氨氯地平联合依那普利治疗原发性高血压的疗效显著,且不良反应较少,值得临床推广。
Objective To observe the clinical efficacy of amlodipine combined with enalapril in the treatment of essential hypertension. Methods A total of 120 patients with primary hypertension admitted to our hospital were randomly divided into two groups. 60 patients in the control group were treated with amlodipine alone. 60 patients in the treatment group were treated with enalapril on the basis of the control group and 4 weeks As a course of treatment, after two courses of treatment compared the efficacy of two groups. Results The blood pressure decreased significantly in the treatment group with a total effective rate of 93.3% and a total effective rate of 71.7% in the control group (P <0.05). The incidence of adverse reactions in the treatment group was 6.7% 15.0%, there was a significant difference between the two groups (P <0.05). Conclusion Amlodipine combined with enalapril treatment of essential hypertension significant effect, and fewer adverse reactions, is worth clinical promotion.