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目的探讨肠道准备对18F-FDG PET/CT显像胃肠道摄取的影响。方法60例PET/CT受检者随机分为肠道准备组和未准备的对照组,每组30例。肠道准备组于检查前1天晚8点服用硫酸镁溶液,静脉注射18F-FDG 20 min后所有检查者分次大量饮水充盈胃肠道;肠道准备组于图像采集前30 min肌肉注射山莨菪碱10 mg。对两组图像的胃、小肠、回盲部、升结肠的18F-FDG摄取进行半定量分析比较。结果肠道准备组与对照组的胃、小肠、升结肠的18F-FDG摄取有较大差异,肠道准备后三者的SUVmax均有明显降低(P<0.01)。结论检查前进行肠道准备可减少18F-FDG PET/CT显像时胃肠道的18F-FDG生理性摄取,有利于正确判读图像,减少假阳性率。
Objective To investigate the effect of intestinal preparation on gastrointestinal uptake in 18F-FDG PET / CT imaging. Methods 60 cases of PET / CT subjects were randomly divided into intestinal preparation group and control group, 30 cases in each group. The gut preparation group took magnesium sulfate solution at 8:00 a day before the test and all the inspectors were given plenty of water to fill the gastrointestinal tract after intravenous injection of 18F-FDG for 20 minutes. The gut preparation group was injected intramuscularly 30 minutes before the image acquisition Scopolamine 10 mg. Semi-quantitative analysis of 18F-FDG uptake in the stomach, small intestine, ileocecal part, and ascending colon of the two groups of images was performed. Results The uptake of 18F-FDG in the stomach, small intestine and ascending colon of the intestinal preparation group was significantly different from that of the control group. The SUVmax of the three groups after intestinal preparation was obviously decreased (P <0.01). Conclusion Preoperative bowel preparation can reduce the physiological intake of 18F-FDG in the gastrointestinal tract during 18F-FDG PET / CT imaging, which helps to interpret the images correctly and reduce the false positive rate.