从肾结石、病理性骨折讲起,联系原发性甲状旁腺机能亢进,讲纤维性囊性骨炎和其它几种代谢性骨疾病(四)

• 作 者: 朱宪彝
• 机 构: 天津医学院,
• 出 处: 天津医药
• 发表日期: 1978年05期
• 关键词: 骨疾病 肾小管功能障碍 骨骼病变 抗维生素 血磷 病理性骨折 血清磷 氨基酸尿 血清碱性磷酸酶 肾小管酸中毒

一、定义肾小管性佝偻病、软骨病是一组由肾小管功能障碍造成的骨骼钙化缺乏疾病,多数为先天性,仅少数为后天。其共同特点是:血清磷低下,尿磷大量流失。骨骼病变仅在部分病人中间出现,在儿童期为佝偻病,成人为软骨病,都属于所谓抗维生素D佝偻病、软骨病。二、分类这一组肾小管性佝偻病、软骨病的肾小管功能障碍多种多样,错综复杂,一般可分为三大组:1.家族性低血磷。2.肾小管性酸中毒。3.范柯尼(Fanconi)氏综合征糖尿、氨基酸尿、低血磷。

First, the definition of tubular rickets, rickets is a group of tubular calcification caused by renal dysfunction disease, mostly congenital, only a few for the day after tomorrow. Its common characteristics are: low serum phosphorus, a large loss of urine phosphorus. Skeletal lesions appear only in some patients, in childhood rickets, adults are rickets, all belong to the so-called anti-vitamin D rickets, rickets. Second, classification This group of tubular rickets, tubular dysfunction of rickets varied, complex, generally divided into three groups: 1. Familial hypophosphatemia. 2. Tubular acidosis. 3. Fanconi’s syndrome, diabetes, amino acid urine, hypophosphatemia.