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目的探讨复治涂阳肺结核合并糖尿病患者的临床特征,以便早期发现,提高疗效。方法回顾性分析北京市通州区疾病预防控制中心2001—2011年间收治的20例复治涂阳肺结核合并糖尿病患者流行病学特征、X线表现、实验室检查及治疗结果。结果复治涂阳肺结核合并糖尿病患者具有中老年男性比例大,病变范围大,易形成空洞,排菌量大,痰菌阴转慢,耐药发生率高,病灶吸收及治疗效果较差的特征。结论复治涂阳肺结核合并糖尿病患者具有一定的临床特征,治疗应积极调控血糖,及时进行药敏试验及合理的抗结核治疗。
Objective To investigate the clinical characteristics of patients with retreated smear-positive pulmonary tuberculosis complicated with diabetes in order to find out early and improve the curative effect. Methods The epidemiological characteristics, X-ray findings, laboratory tests and treatment outcomes of 20 patients with relapsed and smear-positive pulmonary tuberculosis complicated with diabetes treated in Tongzhou District Center for Disease Control and Prevention in Beijing from 2001 to 2011 were retrospectively analyzed. Results Patients with retreatment of smear positive pulmonary tuberculosis and diabetes mellitus had the characteristics of large proportion of middle-aged and elderly men, wide range of disease, easy formation of cavities, large amount of bacteriuria, slow sputum negative conversion, high rate of drug resistance, poor absorption and treatment of lesions . Conclusion Patients with retreatment of smear-positive pulmonary tuberculosis and diabetes mellitus have certain clinical features. The treatment should be active in the regulation of blood glucose, timely drug susceptibility testing and reasonable anti-TB treatment.