稀土钐离子与微过氧化物酶-11的相互作用初探

• 作 者: 李奚 黄晓华 姜慧君 高颖 陆天虹 李邨
• 机 构: 南京师范大学化学与环境科学学院,南京师范大学化学与环境科学学院,南京医科大学基础医学院,哈尔滨师范大学化学系,南京师范大学化学与环境科学学院,南京师范大学化学与环境科学学院 南京210097,南京21
• 出 处: 无机化学学报
• 发表日期: 2003年05期
• 关键词: 微过氧化物酶-11 钐离子 循环伏安法

The interaction between Sm3+and MP 11 in the aqueous solution was investigated with cyclic voltammetry, UV Vis absorption spectrum and circular dichroism. It was found for the first time that Sm3+could bond to O of carboxyl group in the heme group altering the surface charge of MP 11 molecule and thus increasing its diffusion coefficient.In addition, the interaction between Sm3+and MP 11 molecule would change the secondary structure of the MP 11 molecule increasing the exposure extent of the heme group in the MP 11 molecule.The above results could increase the reversibility of the electrochemical reaction of MP 11.

The interaction between Sm3 + and MP 11 in the aqueous solution was investigated with cyclic voltammetry, UV Vis absorption spectrum and circular dichroism. It was found for the first time that Sm3 + could bond to O of carboxyl group in the heme group altering the surface charge of MP 11 molecule and thereby increasing its diffusion coefficient. In addition, the interaction between Sm 11 + and MP 11 molecule would change the secondary structure of the MP 11 molecule increasing exposure area of ​​the heme group in the MP 11 molecule. results could increase the reversibility of the electrochemical reaction of MP 11.