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本文报告了两例合并Graves病的神经性厌食症,文献中尚无报道。 病例1为25岁女性。由于1980年3月流产、5月结婚造成精神压力,出现持续无食欲和体重下降。至1981年1月体重由53kg减至44kg,月经停止。7月体重减至40kg并发现甲状腺肿,但无甲亢症状。10月甲状腺功能检查示明显甲亢。1982年1月体重减至30kg,始就诊于东京大学。患者除甲状腺肿大外无其它甲亢体征和症状,但有低体温、怕冷、心动过缓、低血压和便秘等神经性厌食症的症状。使用心得安和阿托品后心率从70次/分增至108次/分。经用抗甲状腺药物和精神心理治疗,神经性厌食和Grves病均缓解。
This article reports two cases of anorexia nervosa associated with Graves’ disease, which has not been reported in the literature. Case 1 is a 25 year old woman. As a result of the miscarriage in March 1980, stress caused by marriage in May resulted in persistent loss of appetite and weight loss. To January 1981 weight reduced from 53kg 44kg, menstruation stopped. July body weight reduced to 40kg and found goiter, but no symptoms of hyperthyroidism. Thyroid function tests showed hyperthyroidism in October. January 1982 weight reduced to 30kg, first visited the University of Tokyo. Patients with hyperthyroidism outside the absence of other signs and symptoms of hyperthyroidism, but hypothermia, cold, bradycardia, hypotension and constipation and other symptoms of anorexia nervosa. Heart rate after using Ann and atropine increased from 70 beats / min to 108 beats / min. With antithyroid drugs and psychiatric treatment, anorexia nervosa and Grves disease are relieved.