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受体最初由Langley(1878)用来描述细胞上可与药物和其它化学信使物质结合并介导效应的化学成分。近年来对内源性信使物引起作用的不同方式的观察已经将药物的可能作用范围扩大了。目前已能对快和慢递质反应进行区分。 快递质 作用局限、并且可能由于离子通道的快速(如毫秒范围)开放。这包括氨基酸和烟碱样乙酰胆碱的兴奋效应和γ—氨基丁酸(GABA)和甘氨酸的抑制效
Receptors were originally used by Langley (1878) to describe chemical components of cells that bind to drugs and other chemical messenger substances and mediate effects. Recent observations of the different ways in which endogenous messengers contribute have expanded the range of possible effects of the drugs. It is now possible to distinguish between fast and slow astringency. The cortical mass effect is limited and may be due to the fast (eg millisecond range) opening of ion channels. This includes the excitatory effects of amino acids and nicotinic acetylcholine and the inhibitory effect of gamma-aminobutyric acid (GABA) and glycine