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对Ⅱ型糖尿病(NIDDM)的发病学已经进行和正在进行大量的研究。胰岛素分泌对口服或静脉注射葡萄糖的反应、胰岛素结合及胰岛素作用等都曾经在非糖尿病对照者、葡萄糖耐量减低者(IGT)和NIDDM分别进行过观察。尽管从大量研究中得到许多资料,但有关NIDDM的发病原因仍很少有一致的意见,许多研究结果常存在矛盾。不过,作者认为还是有可能建立一个假说来解释当前的大多数资料。
The pathogenesis of type 2 diabetes (NIDDM) has been and is being extensively studied. Insulin secretion in response to oral or intravenous glucose reactions, insulin binding and insulin effects were observed in non-diabetic controls, impaired glucose tolerance (IGT) and NIDDM. Although a great deal of information has been obtained from a large number of studies, there is still very little agreement on the causes of NIDDM, and many studies often contain contradictions. However, the author believes that it is still possible to establish a hypothesis to explain most of the current information.