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泰舒(Chlorotrianlsene、Tace)是上海医药工业研究院和苏州第一制药厂研制成功的一种非甾体雌激素药物,主要治疗妇女更年期综合征、妇女性腺功能不全及前列腺增生等疾患。泰舒化学名:1-氯1、2、2-三(对甲氧基苯基)代乙烯。采用固体分散型制剂——滴丸,吸收和作用迅速完全。作用特点:(1)与其他人工合成雌激素,天然雌激素作用相同,因其活性较已烯雌酚小,属弱雌激素药物,故作用比较温和;(2)口服后能长时间贮藏于脂肪组织内,并逐步释放,故停药后,体内含量只会逐步减少,而不会造成骤然下降,因此作用时间较长,而且耐受性好:(3)据报导泰舒无致癌性,而且能预防和抑制垂体增长而引起的肿瘤和乳腺的原发性肿瘤及治疗前列腺癌的作用;(4)该药安全可靠,经药理试验证实,口服最大耐受量大于10g/kg。
Chlorotrianlsene (Tace) is a non-steroidal estrogen drug successfully developed by Shanghai Institute of Pharmaceutical Industry and Suzhou No. 1 Pharmaceutical Factory. It mainly treats diseases such as climacteric syndrome, gonadal dysfunction and benign prostatic hyperplasia in women. Tissu Chemical name: 1-chloro 1,2,2-tris (p-methoxyphenyl) -vinylidene. With a solid dispersible formulation - dropping pills, absorption and action quickly and completely. Features: (1) with other synthetic estrogen, natural estrogen the same role, because of its activity than diethylstilbestrol is a weak estrogen drugs, so the role of relatively mild; (2) after oral administration can be stored for a long time in Fat tissue, and gradually release, it is discontinued, the body will only gradually reduce the content, but will not result in a sudden decline, so the role of longer, and well tolerated: (3) It is reported that Tishu no carcinogenicity, But also to prevent and inhibit the growth of pituitary tumors and breast caused by the primary tumor and the role of treatment of prostate cancer; (4) The drug is safe and reliable, the pharmacological tests confirmed that the maximum oral tolerance greater than 10g / kg.