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中毒性休克综合征(Toxic Shock Syn-drome,TSS)是一种新认识的严重临床病征,Todd 等1978年首先报道。本综合征以发热、昏厥、低血压或休克、粘膜弥漫性炎症、恶心、呕吐、腹泻及多脏器系统功能障碍等为特征。流行病学调查表明,连续使用月经塞与其发病有联系,但关于中毒性休克的发病机理、金黄色葡萄球菌(下称金葡菌)及其致热外毒素的作用等尚有待阐明。本文拟就国外有关 TSS 的研究近况作一扼要综述。病原学TSS 的病原体是嗜菌体Ⅰ群金葡菌,基本致病因子为其所产生的外毒素,以致热性
Toxic Shock Syn-drome (TSS) is a newly recognized serious clinical symptom, Todd first reported in 1978. The syndrome is characterized by fever, fainting, hypotension or shock, mucosal diffuse inflammation, nausea, vomiting, diarrhea and multiple organ dysfunction. Epidemiological studies have shown that continuous use of menstrual plug and its incidence are linked, but the pathogenesis of toxic shock, Staphylococcus aureus (Staphylococcus aureus) and its role in exothermic exotoxin have yet to be clarified. This article intends to make a brief overview of the current situation of TSS abroad. Pathogen is the pathogen of TSS Staphylococcus aureus mycobacterium group Ⅰ, the basic pathogenic factor for its exotoxin produced, so that the heat