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接种乙型肝炎病毒(hepatitis B virus,HBV)疫苗可有效降低HBV感染率。目前市售HBV疫苗多为以明矾为佐剂的重组HBV表面抗原(rHBsAg)疫苗,该类疫苗具有以下缺点:1)少数人群对其不产生应答;2)产生应答的人群中绝大多数首次免疫后的血清抗体水平较低,需要进行第2或第3次免疫,抗体才
Inoculation of hepatitis B virus (HBV) vaccine can effectively reduce the HBV infection rate. At present, most commercially available HBV vaccines are recombinant HBsAg vaccines adjuvanted with alum. Such vaccines have the following disadvantages: 1) minority populations do not respond to them; 2) most of the responders After the immune serum antibody level is low, need to be the second or the third immunization, antibody only