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欧洲药品管理局人用药品委员会日前对替比夫定与聚乙二醇干扰素联用致周围神经病变风险增加发出警告。替比夫定和聚乙二醇干扰素均可用于治疗慢性活动性乙型肝炎。因此,临床常将该二药联用。替比夫定的常见不良反应有上呼吸道感染、疲劳、腹痛等;偶见周围神经病变,其发生率为0.
The European Medicines Agency’s Commission on Human Medicines has warned of the increased risk of peripheral neuropathy caused by the combination of telbivudine and peginterferon. Telbivudine and peginterferon can be used to treat chronic active hepatitis B. Therefore, the clinical often the two drugs combined. Telbivudine common adverse reactions are upper respiratory tract infection, fatigue, abdominal pain, etc .; occasionally peripheral neuropathy, the incidence rate of 0.