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目的了解耐多药肺结核(MDR-TB)的规则服药依从性现状及影响因素,为实施药学干预提供依据。方法对2010年9月至2014年12月,在福建省CDC第二门诊部治疗并完成24个月全疗程后复诊的167例MDR-TB患者进行问卷调查。结果规则服药依从性好占67.1%。文化程度较高、城镇、经济状况较好、得到家庭支持、有自觉症状、无药物不良反应、结核病知识知晓程度较高及知晓规则服药情况的患者,其规则服药依从性较好,是影响规则服药依从性的主要因素。结论 MDR-TB患者规则服药依从性现状不容乐观,积极开展药学干预,对提高规则服药依从性有积极意义。
OBJECTIVE To understand the status quo and influencing factors of regular medication adherence of multidrug-resistant pulmonary tuberculosis (MDR-TB) and provide basis for the implementation of pharmaceutical intervention. Methods From September 2010 to December 2014, 167 patients with MDR-TB who were referred to the Second Clinic of CDC in Fujian Province and completed the 24-month full course of treatment were surveyed. The results of rule compliance medication accounted for 67.1%. Higher education, better urban living conditions, supportive families, conscious symptoms, no adverse drug reactions, a higher awareness of tuberculosis knowledge and regular medication, patients with better adherence to the rules are the rules of influence The main factor of medication compliance. CONCLUSION: The current compliance status of MDR-TB patients is not optimistic and the pharmacy intervention is actively carried out. It is of great significance to improve the adherence of regular medication.