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本文报告1987年4月对新疆奎屯地方性慢性砷中毒119例五年随访结果。1982年4月曾进行首次调查,1984年10月起当地改良饮用水,其含砷量降至0.045mg/L(原为0.6mg/L),含氟量0.095～1mg/L(原为3.45rag/L)。随访表明,病情好转及痊愈者共88例,占74％,主要表现为砷色素异常的色素沉着消失或减轻,砷角化全部消退者较少。神经系及心血管系症状有所加重。阵发性手足麻木多见,司能与神经炎有关。此外,雷诺氏现象及手足发绀、心电图异常较常见。发现皮肤癌4例,基底细胞上皮瘤3例,表皮内鳞癌l例,迄今尚未见内脏恶性肿瘤病例。本组2例死亡,死因与砷中毒的关系有待进一步研究。本组伴发氟中毒18例,与砷中毒有无协同或拮抗作用尚待观察。
This article reports the results of five-year follow-up of 119 cases of endemic chronic arsenic poisoning in Kuitun, Xinjiang in April 1987. In April 1982, the first survey was conducted. Since October 1984, drinking water has been locally modified to reduce the arsenic content to 0.045mg / L (formerly 0.6mg / L) and the fluoride content to 0.095-1mg / L (originally 3.45 rag / L). Follow-up showed that the condition improved and healed a total of 88 cases, accounting for 74%, mainly as a pigmentation abnormalities disappear or reduce arsenic, arsenic all subsided less. Neurological and cardiovascular symptoms have increased. Paroxysmal numbness more common hand, Secretary and neuritis related. In addition, Raynaud’s phenomenon and cyanosis, ECG abnormalities are more common. Found in 4 cases of skin cancer, basal cell epithelial tumor in 3 cases, squamous cell carcinoma in l cases, so far no cases of visceral malignancy. The two cases of death, the cause of death and arsenic poisoning needs further study. This group of 18 cases of fluorosis accompanied by fluoride, with or without arsenic poisoning antagonism remains to be seen.