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目的 :探讨高原低氧环境健康移居人群心肌细胞的影响。方法 :采用双抗体夹心ELISA测定海拔 4 70 0m地区 10 0名健康男性 (部队官兵 )的心肌肌钙蛋白I(cTnI)含量。结果 :10 0名健康男性血清cTnI测定值均 >10 0 0ng/L ,平均为 (1370± 180 )ng/L ,与该方法正常人参考值比较 ,差别有显著性 (P <0 .0 1)。结论 :在高原低氧环境中 ,健康移居人群的心肌细胞存在一定程度的损伤。
Objective: To investigate the effect of platelet hypoxic environment on healthy migrants. Methods: The cardiac troponin I (cTnI) levels in 10 0 healthy men (military officers and men) at 4 700 m altitude were measured by double antibody sandwich ELISA. Results: The serum levels of cTnI in all 10 healthy men were> 10 0 ng / L with an average of (1370 ± 180) ng / L, which was significantly different from the normal reference value of this method (P <0.01 ). CONCLUSION: Myocardial cells in healthy migrants have a certain degree of damage in plateau hypoxia.