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目的 探讨细菌 L型医院感染率、病原学特点及临床特征。方法 对住院病人采用前瞻性监测 ;进行细菌 L型培养 ,并采用 K- B法进行药敏试验。结果 71 2 4例住院病人中 ,细菌 L型感染 1 2 6例 ( 1 .77% ) ,烧伤科感染率最高 ,占 9.0 0 % ,其次是肾科 ( 7.1 9% )、血液科 ( 5.1 3% )及小儿科 ( 3.53% )。下呼吸道感染最常见 ( 39.6% ) ,呼吸道症状不典型 ,但受累肺野≥ 2个者占 86.5%。尿路感染者菌落计数 >1× 1 0 5CFU/ ml者占 3.8%。共分离出 1 48株细菌 L型 ,常见的菌种是金葡菌( 2 5.7% ) ,其次为大肠埃希菌和铜绿假单胞菌 (各占 1 6.7% ) ;各种细菌 L型对青霉素、头孢菌素类耐药率高。1 2 6例中治愈 1 0 9例 ,死亡 6例。结论 细菌 L型医院感染临床上常见 ,表现不典型 ,耐药性严重。
Objective To investigate the infection rate, etiological characteristics and clinical features of bacterial L-type hospital. Methods The hospitalized patients were prospectively monitored. Bacterial L-type cultures were cultured and K-B method was used for susceptibility testing. Results Among 71 24 inpatients, 126 (1.77%) were bacterial L-forms and the highest infection rate was 9.0 0%, followed by nephrology (7.19%), hematology (5.13 %) And pediatric (3.53%). Lower respiratory tract infection is the most common (39.6%), respiratory symptoms are not typical, but the involvement of the lung field ≥ 2 accounted for 86.5%. Urinary tract infection colony count> 1 × 105CFU / ml accounted for 3.8%. A total of 148 isolates of L type were isolated. Staphylococcus aureus (25.7%) was common, followed by Escherichia coli and Pseudomonas aeruginosa (1 6.7% each) Penicillin, cephalosporins resistant rate is high. In 126 cases, 109 cases were cured and 6 died. Conclusion Bacterial L-type hospital infection is clinically common, with atypical performance and serious drug resistance.